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Merck agrees US$6.7bn deal for Terns Pharmaceuticals

The all-cash takeover hands Merck an oral leukaemia candidate as it looks to broaden its oncology pipeline ahead of Keytruda's patent expiry.

M&A News deals deskHealthcare / Biotech · United States, Americas25 Mar 2026

Merck agreed on 25 March 2026 to acquire Terns Pharmaceuticals, a clinical-stage oncology company based in Foster City, California, for US$53.00 per share in cash, giving the deal an equity value of about US$6.7bn.

Terns Pharmaceuticals website: ternspharma.com

Why Merck & Co., Inc. is buying Terns Pharmaceuticals, Inc.

Merck said Terns' lead candidate TERN-701, an investigational oral allosteric BCR::ABL1 tyrosine kinase inhibitor in the Phase 1/2 CARDINAL trial, builds on its growing presence in haematology. The company described the drug as a potential best-in-class option for certain patients with chronic myeloid leukaemia.

“The acquisition of Terns builds on our growing presence in hematology with TERN-701, a potential best-in-class candidate for the treatment of certain patients with chronic myeloid leukemia.”Robert M. Davis, chairman and chief executive officer, Merck

Deal terms and financing

The price was about 31% above Terns' 60-day and 42% above its 90-day volume-weighted average share price to 24 March. Net of acquired cash the deal was worth about US$5.7bn. It was structured as a tender offer by a Merck subsidiary followed by a merger, and was expected to be accounted for as an asset acquisition with a charge of about US$5.8bn, or US$2.35 per share.

Regulatory approvals and timing

Closing required a majority of Terns shares to be tendered and expiry of the US Hart-Scott-Rodino waiting period. The tender offer expired on 4 May with about 86.4% of shares tendered, and Merck announced on 5 May 2026 that the acquisition was complete and Terns had been delisted from Nasdaq.

Market context

Merck is looking for new growth drivers as Keytruda, its top-selling cancer drug, nears patent expiry. The deal followed its 2025 agreements to buy Verona Pharma and Cidara Therapeutics. Merck's later quarterly filing lists the drug as MK-4208.

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